Knockdown of the Ribosomal Protein eL29 in Mammalian Cells Leads to Significant Changes in Gene Expression at the Transcription Level

Knockdown of the Ribosomal Protein eL29 in Mammalian Cells Leads to Significant Changes in Gene Expression at the Transcription Level

An imbalance in the synthesis of ribosomal proteins can lead to the disruption of various cellular processes. For mammalian cells, it has been shown that the level of the eukaryote-specific ribosomal protein eL29, also known as the one interacting with heparin/heparan sulfate, substantially affects...

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Bibliographic Details
Main Authors: Alexander V. Gopanenko, Alena V. Kolobova, Maria I. Meschaninova, Alya G. Venyaminova, Alexey E. Tupikin, Marsel R. Kabilov, Alexey A. Malygin, Galina G. Karpova
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
HEK293 cells
knockdown of ribosomal protein eL29
next-generation sequencing
RNA-seq
differential gene expression
eL29-dependent genes
Online Access:https://www.mdpi.com/2073-4409/9/5/1228

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https://www.mdpi.com/2073-4409/9/5/1228

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