Successful management of acute graft-versus-host disease with ibrutinib during cord blood transplantation for germline DDX41-mutated acute myeloid leukemia

Background: Acute graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT) with significant morbidity and mortality, and efficacy of currently available therapeutics are limited. Acute and chronic GVHD are similar in that both are ini...

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Bibliographic Details
Main Authors:	Ayana Uchimura, Hajime Yasuda, Hiroko Onagi, Tadaaki Inano, Shuichi Shirane, Midori Ishii, Yoko Azusawa, Yasuharu Hamano, Hidetaka Eguchi, Masami Arai, Jun Ando, Miki Ando
Format:	Article
Language:	English
Published:	Elsevier 2024-01-01
Series:	Heliyon
Subjects:	Allogeneic hematopoietic stem cell transplantation (allo-HSCT, allo-SCT) DEAD-Box RNA helicase 41 (DDX41) Myeloid neoplasms with germline predisposition Hereditary hematologic malignancies (HHM) Familial myelodysplastic syndrome (MDS) / acute myeloid leukemia (AML) Severe gastrointestinal graft-versus-host-disease (GVHD)
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844024008326

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http://www.sciencedirect.com/science/article/pii/S2405844024008326

Successful management of acute graft-versus-host disease with ibrutinib during cord blood transplantation for germline DDX41-mutated acute myeloid leukemia

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