Venetoclax combined with daunorubicin and cytarabine (2 + 6) as induction treatment in adults with newly diagnosed acute myeloid leukemia: a phase 2, multicenter, single-arm trial

Venetoclax combined with daunorubicin and cytarabine (2 + 6) as induction treatment in adults with newly diagnosed acute myeloid leukemia: a phase 2, multicenter, single-arm trial

Abstract Background Venetoclax (Ven) combined with intensive chemotherapy was proven effective in the management of acute myeloid leukemia (AML). However, the severe and prolonged myelosuppression remains a concern to worry about. To explore more appropriate combination regimens, we designed Ven com...

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Bibliographic Details
Main Authors: Xiaohui Suo, Fang Zheng, Dongmei Wang, Liyun Zhao, Jie Liu, Ling Li, Zhihua Zhang, Congcong Zhang, Yinling Li, Sisi Yang, Xuemei Zhao, Rui Shi, Yan Wu, Zongjiu Jiao, Jiaojie Song, Ling Zhang, Xinxiao Lu, Linyu Yuan, Sifeng Gao, Jilei Zhang, Xingli Zhao, Guanchen Bai, Kaiqi Liu, Yingchang Mi
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Experimental Hematology & Oncology
Subjects:
Venetoclax
DA
Induction treatment
Acute myeloid leukemia
Online Access:https://doi.org/10.1186/s40164-023-00409-y

Internet

https://doi.org/10.1186/s40164-023-00409-y

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