New insights into the mechanism of action of pyrazinamide, implications for susceptibility testing, and future regimens*

New insights into the mechanism of action of pyrazinamide, implications for susceptibility testing, and future regimens*

Pyrazinamide (PZA) is included in the 2016 World Health Organization multidrug-resistant tuberculosis treatment guidelines and is a key component of most ongoing clinical trials investigating novel antibiotic combinations. PZA resistance is associated with worse tuberculosis treatment outcomes. Unfo...

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Bibliographic Details
Main Authors: Richard M Anthony, Alice den Hertog, Mikael Mansjö, Jim Werngren
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:International Journal of Mycobacteriology
Subjects:
MDR-TB
Pyrazinamide
Online Access:http://www.ijmyco.org/article.asp?issn=2212-5531;year=2016;volume=5;issue=5;spage=71;epage=72;aulast=Anthony

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http://www.ijmyco.org/article.asp?issn=2212-5531;year=2016;volume=5;issue=5;spage=71;epage=72;aulast=Anthony

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