Numb Suppresses Notch-Dependent Activation of <i>Enhancer of split</i> during Lateral Inhibition in the <i>Drosophila</i> Embryonic Nervous System

Numb Suppresses Notch-Dependent Activation of <i>Enhancer of split</i> during Lateral Inhibition in the <i>Drosophila</i> Embryonic Nervous System

The role of <i>Drosophila numb</i> in regulating Notch signaling and neurogenesis has been extensively studied, with a particular focus on its effects on the peripheral nervous system (PNS). Previous studies based on a single loss-of-function allele of <i>numb</i>, <i>n...

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Bibliographic Details
Main Authors: Elzava Yuslimatin Mujizah, Satoshi Kuwana, Kenjiroo Matsumoto, Takuma Gushiken, Naoki Aoyama, Hiroyuki O. Ishikawa, Takeshi Sasamura, Daiki Umetsu, Mikiko Inaki, Tomoko Yamakawa, Martin Baron, Kenji Matsuno
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Biomolecules
Subjects:
Notch
<i>numb</i>
<i>Enhancer of split</i>
neurogenesis
lateral inhibition
neurogenic phenotype
Online Access:https://www.mdpi.com/2218-273X/14/9/1062

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https://www.mdpi.com/2218-273X/14/9/1062

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