Imputation of Human Primary Osteoblast Single Cell RNA-Seq Data Identified Three Novel Osteoblastic Subtypes

Imputation of Human Primary Osteoblast Single Cell RNA-Seq Data Identified Three Novel Osteoblastic Subtypes

Background: Recently, single-cell RNA sequencing (scRNA-seq) technology was increasingly used to study transcriptomics at a single-cell resolution, scRNA-seq analysis was complicated by the “dropout”, where the data only captures a small fraction of the transcriptome. This phenomenon can lead to the...

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Bibliographic Details
Main Authors: Hui-Xi Zhang, Chong Cao, Xiao-Hua Li, Yan Chen, Yue Zhang, Ying Liu, Yun Gong, Xiang Qiu, Cui Zhou, Yu Chen, Zun Wang, Jun-Xiao Yang, Liang Cheng, Xiang-Ding Chen, Hui Shen, Hong-Mei Xiao, Li-Jun Tan, Hong-Wen Deng
Format: Article
Language:English
Published: IMR Press 2022-10-01
Series:Frontiers in Bioscience-Landmark
Subjects:
single-cell rna sequencing (scrna-seq)
imputation
osteoblast heterogeneity
immune regulation
osteoclast differentiation
adipose differentiation
Online Access:https://www.imrpress.com/journal/FBL/27/10/10.31083/j.fbl2710295

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https://www.imrpress.com/journal/FBL/27/10/10.31083/j.fbl2710295

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