The Highest Density of Phosphorylated Histone H1 Appeared in Prophase and Prometaphase in Parallel with Reduced H3K9me3, and HDAC1 Depletion Increased H1.2/H1.3 and H1.4 Serine 38 Phosphorylation

Background: Variants of linker histone H1 are tissue-specific and are responsible for chromatin compaction accompanying cell differentiation, mitotic chromosome condensation, and apoptosis. Heterochromatinization, as the main feature of these processes, is also associated with pronounced trimethylat...

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Bibliographic Details
Main Authors: Soňa Legartová, Gabriela Lochmanová, Eva Bártová
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/12/6/798