Fetal testis organ culture reproduces the dynamics of epigenetic reprogramming in rat gonocytes

Abstract Background Epigenetic reprogramming is a critical step in male germ cell development that occurs during perinatal life. It is characterized by the remodeling of different epigenetic marks such as DNA methylation (5mC) and methylation of histone H3. It has been suggested that endocrine disru...

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Bibliographic Details
Main Authors: Arlette Rwigemera, Fabien Joao, Geraldine Delbes
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13072-017-0127-3