Effect of Lacking ZKSCAN3 on Autophagy, Lysosomal Biogenesis and Senescence

Effect of Lacking ZKSCAN3 on Autophagy, Lysosomal Biogenesis and Senescence

Transcription factors can affect autophagy activity by promoting or inhibiting the expression of autophagic and lysosomal genes. As a member of the zinc finger family DNA-binding proteins, ZKSCAN3 has been reported to function as a transcriptional repressor of autophagy, silencing of which can induc...

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Bibliographic Details
Main Authors: Xiao-Min Li, Jun-Hao Wen, Ze-Sen Feng, Yun-Shan Wu, Dong-Yi Li, Shan Liang, Dan Wu, Hong-Luan Wu, Shang-Mei Li, Zhen-Nan Ye, Chen Yang, Lin Sun, Ji-Xin Tang, Hua-Feng Liu
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
ZKSCAN3
autophagy
lysosomal biogenesis
senescence
CRISPR/Cas9
transcriptome sequencing
Online Access:https://www.mdpi.com/1422-0067/24/9/7786

Internet

https://www.mdpi.com/1422-0067/24/9/7786

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