A Comparison of Intramuscular and Subcutaneous Administration of LigA Subunit Vaccine Adjuvanted with Neutral Liposomal Formulation Containing Monophosphoryl Lipid A and QS21

A Comparison of Intramuscular and Subcutaneous Administration of LigA Subunit Vaccine Adjuvanted with Neutral Liposomal Formulation Containing Monophosphoryl Lipid A and QS21

Leptospirosis vaccines with higher potency and reduced adverse effects are needed for human use. The carboxyl terminal domain of leptospiral immunoglobulin like protein A (LigAc) is currently the most promising candidate antigen for leptospirosis subunit vaccine. However, LigAc-based vaccines were u...

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Bibliographic Details
Main Authors: Teerasit Techawiwattanaboon, Christophe Barnier-Quer, Tanapat Palaga, Alain Jacquet, Nicolas Collin, Noppadon Sangjun, Pat Komanee, Kanitha Patarakul
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Vaccines
Subjects:
leptospirosis
<i>Leptospira</i>
LigA subunit vaccine
LMQ adjuvant
vaccination route
intramuscular
Online Access:https://www.mdpi.com/2076-393X/8/3/494

Internet

https://www.mdpi.com/2076-393X/8/3/494

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