Development and validation of a 36-gene sequencing assay for hereditary cancer risk assessment

Development and validation of a 36-gene sequencing assay for hereditary cancer risk assessment

The past two decades have brought many important advances in our understanding of the hereditary susceptibility to cancer. Numerous studies have provided convincing evidence that identification of germline mutations associated with hereditary cancer syndromes can lead to reductions in morbidity and...

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Bibliographic Details
Main Authors: Valentina S. Vysotskaia, Gregory J. Hogan, Genevieve M. Gould, Xin Wang, Alex D. Robertson, Kevin R. Haas, Mark R. Theilmann, Lindsay Spurka, Peter V. Grauman, Henry H. Lai, Diana Jeon, Genevieve Haliburton, Matt Leggett, Clement S. Chu, Kevin Iori, Jared R. Maguire, Kaylene Ready, Eric A. Evans, Hyunseok P. Kang, Imran S. Haque
Format: Article
Language:English
Published: PeerJ Inc. 2017-02-01
Series:PeerJ
Subjects:
Hereditary cancer
Multigene panel testing
Next generation sequencing
Analytical validation
Online Access:https://peerj.com/articles/3046.pdf

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https://peerj.com/articles/3046.pdf

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