GAS6/TAM signaling pathway controls MICA expression in multiple myeloma cells

GAS6/TAM signaling pathway controls MICA expression in multiple myeloma cells

NKG2D ligands play a relevant role in Natural Killer (NK) cell -mediated immune surveillance of multiple myeloma (MM). Different levels of regulation control the expression of these molecules at cell surface. A number of oncogenic proteins and miRNAs act as negative regulators of NKG2D ligand transc...

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Bibliographic Details
Main Authors: Andrea Kosta, Abdelilah Mekhloufi, Lorenzo Lucantonio, Alessandra Zingoni, Alessandra Soriani, Marco Cippitelli, Angela Gismondi, Francesca Fazio, Maria Teresa Petrucci, Angela Santoni, Helena Stabile, Cinzia Fionda
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
GAS6
AXL
MERTK
MICA
NKG2D ligand
multiple myeloma
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.942640/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.942640/full

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