pp32 and APRIL are host cell-derived regulators of influenza virus RNA synthesis from cRNA

pp32 and APRIL are host cell-derived regulators of influenza virus RNA synthesis from cRNA

Replication of influenza viral genomic RNA (vRNA) is catalyzed by viral RNA-dependent RNA polymerase (vRdRP). Complementary RNA (cRNA) is first copied from vRNA, and progeny vRNAs are then amplified from the cRNA. Although vRdRP and viral RNA are minimal requirements, efficient cell-free replication...

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Bibliographic Details
Main Authors: Kenji Sugiyama, Atsushi Kawaguchi, Mitsuru Okuwaki, Kyosuke Nagata
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-10-01
Series:eLife
Subjects:
ANP32
de novo
host factor
influenza
replication
RNA dependent RNA polymerase
Online Access:https://elifesciences.org/articles/08939

Internet

https://elifesciences.org/articles/08939

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