High‐Fat‐Diet Intake Enhances Cerebral Amyloid Angiopathy and Cognitive Impairment in a Mouse Model of Alzheimer's Disease, Independently of Metabolic Disorders

BackgroundThe high‐fat Western diet is postulated to be associated with the onset and progression of Alzheimer's disease (AD). However, the role of high‐fat‐diet consumption in AD pathology is unknown. This study was undertaken to examine the role of high‐fat‐diet intake in AD. Methods and Resu...

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Bibliographic Details
Main Authors: Bowen Lin, Yu Hasegawa, Koki Takane, Nobutaka Koibuchi, Cheng Cao, Shokei Kim‐Mitsuyama
Format: Article
Language:English
Published: Wiley 2016-06-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.115.003154