Long-Chain Omega-3 Fatty Acids Supplementation Accelerates Nerve Regeneration and Prevents Neuropathic Pain Behavior in Mice

Long-Chain Omega-3 Fatty Acids Supplementation Accelerates Nerve Regeneration and Prevents Neuropathic Pain Behavior in Mice

Fish oil (FO) is the main source of long chain omega-3 polyunsaturated fatty acids (ω-3 PUFAs), which display relevant analgesic and anti-inflammatory properties. Peripheral nerve injury is driven by degeneration, neuroinflammation, and neuronal plasticity which results in neuropathic pain (NP) symp...

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Bibliographic Details
Main Authors: Rafaela V. Silva, Julia T. Oliveira, Bruna L. R. Santos, Fabiana C. Dias, Ana M. B. Martinez, Cleverton K. F. Lima, Ana L. P. Miranda
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Pharmacology
Subjects:
omega-3 PUFA
neuropathic pain
fish oil
nerve regeneration
peripheral nerve injury
docosahexaenoic acid
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00723/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00723/full

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