Slc38a1 Conveys Astroglia-Derived Glutamine into GABAergic Interneurons for Neurotransmitter GABA Synthesis

Slc38a1 Conveys Astroglia-Derived Glutamine into GABAergic Interneurons for Neurotransmitter GABA Synthesis

GABA signaling is involved in a wide range of neuronal functions, such as synchronization of action potential firing, synaptic plasticity and neuronal development. Sustained GABA signaling requires efficient mechanisms for the replenishment of the neurotransmitter pool of GABA. The prevailing theory...

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Bibliographic Details
Main Authors: Tayyaba Qureshi, Mona Bjørkmo, Kaja Nordengen, Vidar Gundersen, Tor Paaske Utheim, Leiv Otto Watne, Jon Storm-Mathisen, Bjørnar Hassel, Farrukh Abbas Chaudhry
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
astrocyte-neuron shuttle
GABA
glutamate
glutamine transporter
interneuron
neurotransmitter replenishment
Online Access:https://www.mdpi.com/2073-4409/9/7/1686

Internet

https://www.mdpi.com/2073-4409/9/7/1686

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