Ligand-induced tyrosine phosphorylation of cysteinyl leukotriene receptor 1 triggers internalization and signaling in intestinal epithelial cells.

<h4>Background</h4>Leukotriene D(4) (LTD(4)) belongs to the bioactive lipid group known as eicosanoids and has implications in pathological processes such as inflammation and cancer. Leukotriene D(4) exerts its effects mainly through two different G-protein-coupled receptors, CysLT(1) an...

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Détails bibliographiques
Auteurs principaux: Ladan Parhamifar, Wondossen Sime, Yuliana Yudina, Frederik Vilhardt, Matthias Mörgelin, Anita Sjölander
Format: Article
Langue:English
Publié: Public Library of Science (PLoS) 2010-12-01
Collection:PLoS ONE
Accès en ligne:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21203429/?tool=EBI