Modulation of the beta-catenin signaling pathway by the dishevelled-associated protein Hipk1.

BACKGROUND:Wnts are evolutionarily conserved ligands that signal through beta-catenin-dependent and beta-catenin-independent pathways to regulate cell fate, proliferation, polarity, and movements during vertebrate development. Dishevelled (Dsh/Dvl) is a multi-domain scaffold protein required for vir...

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Bibliographic Details
Main Authors: Sarah H Louie, Xiao Yong Yang, William H Conrad, Jeanot Muster, Stephane Angers, Randall T Moon, Benjamin N R Cheyette
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2629544?pdf=render