The Role of Pyrazolo[3,4-d]pyrimidine-Based Kinase Inhibitors in The Attenuation of CCl<sub>4</sub>-Induced Liver Fibrosis in Rats

The Role of Pyrazolo[3,4-d]pyrimidine-Based Kinase Inhibitors in The Attenuation of CCl<sub>4</sub>-Induced Liver Fibrosis in Rats

Liver Fibrosis can be life-threatening if left untreated as it may lead to serious, incurable complications. The common therapeutic approach is to reverse the fibrosis while the intervention is still applicable. Celecoxib was shown to exhibit some antifibrotic properties in the induced fibrotic live...

Full description

Bibliographic Details
Main Authors: Diana K. Ghobrial, Nefertiti El-Nikhely, Eman Sheta, Hanan M. Ragab, Sherif A. F. Rostom, Hesham Saeed, Ahmed Wahid
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Antioxidants
Subjects:
liver fibrosis
celecoxib
kinase inhibitor
pyrazolo[3,4-d]pyrimidine
TGF-β
Online Access:https://www.mdpi.com/2076-3921/12/3/637

Internet

https://www.mdpi.com/2076-3921/12/3/637

Similar Items