Availability of Central α4β2* Nicotinic Acetylcholine Receptors in Human Obesity

Availability of Central α4β2* Nicotinic Acetylcholine Receptors in Human Obesity

Purpose: Obesity is thought to arise, in part, from deficits in the inhibitory control over appetitive behavior. Such motivational processes are regulated by neuromodulators, specifically acetylcholine (ACh), via α4β2* nicotinic ACh receptors (nAChR). These nAChR are highly enriched in the thalamus...

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Bibliographic Details
Main Authors: Eva Schweickert de Palma, Tilman Günnewig, Michael Rullmann, Julia Luthardt, Mohammed K. Hankir, Philipp M. Meyer, Georg-Alexander Becker, Marianne Patt, Sarah Martin, Anja Hilbert, Matthias Blüher, Osama Sabri, Swen Hesse
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Brain Sciences
Subjects:
obesity
PET
acetylcholine
nicotinic receptors
(−)-[<sup>18</sup>F]flubatine
nucleus basalis of Meynert
Online Access:https://www.mdpi.com/2076-3425/12/12/1648

Internet

https://www.mdpi.com/2076-3425/12/12/1648

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