Plasmodium vivax invasion of human erythrocytes inhibited by antibodies directed against the Duffy binding protein.
BACKGROUND:Plasmodium vivax invasion requires interaction between the human Duffy antigen on the surface of erythrocytes and the P. vivax Duffy binding protein (PvDBP) expressed by the parasite. Given that Duffy-negative individuals are resistant and that Duffy-negative heterozygotes show reduced su...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-12-01
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Series: | PLoS Medicine |
Online Access: | http://europepmc.org/articles/PMC2140086?pdf=render |