Edge-based relative entropy as a sensitive indicator of critical transitions in biological systems
Abstract Background Disease progression in biosystems is not always a steady process but is occasionally abrupt. It is important but challenging to signal critical transitions in complex biosystems. Methods In this study, based on the theoretical framework of dynamic network biomarkers (DNBs), we pr...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-04-01
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| Series: | Journal of Translational Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12967-024-05145-3 |