Sex differences in the genetic regulation of the blood transcriptome response to glucocorticoid receptor activation

Abstract Substantial sex differences have been reported in the physiological response to stress at multiple levels, including the release of the stress hormone, cortisol. Here, we explore the genomic variants in 93 females and 196 males regulating the initial transcriptional response to cortisol via...

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Bibliographic Details
Main Authors: Sarah R. Moore, Thorhildur Halldorsdottir, Jade Martins, Susanne Lucae, Bertram Müller-Myhsok, Nikola S. Müller, Charlotte Piechaczek, Lisa Feldmann, Franz Joseph Freisleder, Ellen Greimel, Gerd Schulte-Körne, Elisabeth B. Binder, Janine Arloth
Format: Article
Language:English
Published: Nature Publishing Group 2021-12-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01756-2