TAD cliques predict key features of chromatin organization

Abstract Background Mechanisms underlying genome 3D organization and domain formation in the mammalian nucleus are not completely understood. Multiple processes such as transcriptional compartmentalization, DNA loop extrusion and interactions with the nuclear lamina dynamically act on chromatin at m...

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Bibliographic Details
Main Authors: Tharvesh M. Liyakat Ali, Annaël Brunet, Philippe Collas, Jonas Paulsen
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-021-07815-8