Opportunities and Challenges for In Silico Drug Discovery at Delta Opioid Receptors

Opportunities and Challenges for In Silico Drug Discovery at Delta Opioid Receptors

The delta opioid receptor is a Gi-protein-coupled receptor (GPCR) with a broad expression pattern both in the central nervous system and the body. The receptor has been investigated as a potential target for a multitude of significant diseases including migraine, alcohol use disorder, ischemia, and...

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Bibliographic Details
Main Authors: Yazan J. Meqbil, Richard M. van Rijn
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pharmaceuticals
Subjects:
mutagenesis
artificial intelligence
computer-aided drug design
molecular dynamic simulation
biased signaling
G protein-coupled receptor
Online Access:https://www.mdpi.com/1424-8247/15/7/873

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https://www.mdpi.com/1424-8247/15/7/873

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