Neural mechanism of acute stress regulation by trace aminergic signalling in the lateral habenula in male mice

Abstract Stress management is necessary for vertebrate survival. Chronic stress drives depression by excitation of the lateral habenula (LHb), which silences dopaminergic neurons in the ventral tegmental area (VTA) via GABAergic neuronal projection from the rostromedial tegmental nucleus (RMTg). How...

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Bibliographic Details
Main Authors: Soo Hyun Yang, Esther Yang, Jaekwang Lee, Jin Yong Kim, Hyeijung Yoo, Hyung Sun Park, Jin Taek Jung, Dongmin Lee, Sungkun Chun, Yong Sang Jo, Gyeong Hee Pyeon, Jae-Yong Park, Hyun Woo Lee, Hyun Kim
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38180-7