Co-crystal Structure of Thermosynechococcus elongatus Sucrose Phosphate Synthase With UDP and Sucrose-6-Phosphate Provides Insight Into Its Mechanism of Action Involving an Oxocarbenium Ion and the Glycosidic Bond

Co-crystal Structure of Thermosynechococcus elongatus Sucrose Phosphate Synthase With UDP and Sucrose-6-Phosphate Provides Insight Into Its Mechanism of Action Involving an Oxocarbenium Ion and the Glycosidic Bond

In green species, sucrose can help antagonize abiotic stress. Sucrose phosphate synthase (SPS) is a well-known rate-limiting enzyme in the synthesis of sucrose. To date, however, there is no known crystal structure of SPS from plant or cyanobacteria. In this study, we report the first co-crystal str...

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Bibliographic Details
Main Authors: Yuying Li, Yuan Yao, Guosong Yang, Jun Tang, Gabriela Jaramillo Ayala, Xumin Li, Wenlu Zhang, Qiuyu Han, Tong Yang, Hao Wang, Kevin H. Mayo, Jiyong Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Microbiology
Subjects:
sucrose phosphate synthase
Thermosynechococcus elongatus
UDP
sucrose-6-phosphate
oxocarbenium ion
glycosidic bond
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01050/full

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https://www.frontiersin.org/article/10.3389/fmicb.2020.01050/full

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