EF-hand protein, EfhP, specifically binds Ca2+ and mediates Ca2+ regulation of virulence in a human pathogen Pseudomonas aeruginosa

EF-hand protein, EfhP, specifically binds Ca2+ and mediates Ca2+ regulation of virulence in a human pathogen Pseudomonas aeruginosa

Abstract Calcium (Ca2+) is well known as a second messenger in eukaryotes, where Ca2+ signaling controls life-sustaining cellular processes. Although bacteria produce the components required for Ca2+ signaling, little is known about the mechanisms of bacterial Ca2+ signaling. Previously, we have ide...

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Bibliographic Details
Main Authors: Biraj B. Kayastha, Aya Kubo, Jacob Burch-Konda, Rosalie L. Dohmen, Jacee L. McCoy, Rendi R. Rogers, Sergio Mares, Justin Bevere, Annalisa Huckaby, William Witt, Shuxia Peng, Bharat Chaudhary, Smita Mohanty, Mariette Barbier, Gabriel Cook, Junpeng Deng, Marianna A. Patrauchan
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-12584-9

Internet

https://doi.org/10.1038/s41598-022-12584-9

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