Live Brugia malayi microfilariae inhibit transendothelial migration of neutrophils and monocytes.

Lymphatic filariasis is a major tropical disease caused by the parasite Brugia malayi. Microfilariae (Mf) circulate in the peripheral blood for 2-3 hours in synchronisation with maximal feeding of the mosquito vector. When absent from the peripheral blood, Mf sequester in the capillaries of the lung...

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Bibliographic Details
Main Authors: Jan-Hendrik Schroeder, Bigboy H Simbi, Louise Ford, Sara R Cole, Mark J Taylor, Charlotte Lawson, Rachel A Lawrence
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0001914&type=printable