Commentary on 2022 guidelines on clinical trial design in cluster headache and further suggestions

Abstract Background New guidelines for cluster headache clinical trials were recently published. We welcome these new guidelines and raise additional considerations in trial methodologies. Main body We present non-inferiority trials to overcome ethical issues with placebo use, and additionally discu...

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Bibliographic Details
Main Authors: Ioana Medrea, Stewart J. Tepper, Donliang Wang, Paul G. Mathew, Mark Burish
Format: Article
Language:English
Published: BMC 2024-03-01
Series:The Journal of Headache and Pain
Subjects:
Online Access:https://doi.org/10.1186/s10194-024-01732-3