Commentary on 2022 guidelines on clinical trial design in cluster headache and further suggestions
Abstract Background New guidelines for cluster headache clinical trials were recently published. We welcome these new guidelines and raise additional considerations in trial methodologies. Main body We present non-inferiority trials to overcome ethical issues with placebo use, and additionally discu...
Main Authors: | Ioana Medrea, Stewart J. Tepper, Donliang Wang, Paul G. Mathew, Mark Burish |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-03-01
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Series: | The Journal of Headache and Pain |
Subjects: | |
Online Access: | https://doi.org/10.1186/s10194-024-01732-3 |
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