SPIRAL: integrating and aligning spatially resolved transcriptomics data across different experiments, conditions, and technologies

SPIRAL: integrating and aligning spatially resolved transcriptomics data across different experiments, conditions, and technologies

Abstract Properly integrating spatially resolved transcriptomics (SRT) generated from different batches into a unified gene-spatial coordinate system could enable the construction of a comprehensive spatial transcriptome atlas. Here, we propose SPIRAL, consisting of two consecutive modules: SPIRAL-i...

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Bibliographic Details
Main Authors: Tiantian Guo, Zhiyuan Yuan, Yan Pan, Jiakang Wang, Fengling Chen, Michael Q. Zhang, Xiangyu Li
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-023-03078-6

Internet

https://doi.org/10.1186/s13059-023-03078-6

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