Functional neuromuscular junctions formed by embryonic stem cell-derived motor neurons.

A key objective of stem cell biology is to create physiologically relevant cells suitable for modeling disease pathologies in vitro. Much progress towards this goal has been made in the area of motor neuron (MN) disease through the development of methods to direct spinal MN formation from both embry...

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Bibliographic Details
Main Authors: Joy A Umbach, Katrina L Adams, Cameron B Gundersen, Bennett G Novitch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3344836?pdf=render