Efficient bioactive oligonucleotide‐protein conjugation for cell‐targeted cancer therapy
Abstract Oligonucleotide‐protein conjugates have important applications in biomedicine. Simple and efficient methods are described for the preparation of these conjugates. Specifically, we describe a new method in which a bifunctional linker is attached to thiol‐oligonucleotide to generate a reactiv...
Main Authors: | Dr. Anna Aviñó, Dr. Ugutz Unzueta, Dr. María Virtudes Céspedes, Dr. Isolda Casanova, Dr. Esther Vázquez, Prof. Dr. Antonio Villaverde, Prof. Dr. Ramon Mangues, Prof. Dr. Ramon Eritja |
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Format: | Article |
Language: | English |
Published: |
Wiley-VCH
2019-03-01
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Series: | ChemistryOpen |
Subjects: | |
Online Access: | https://doi.org/10.1002/open.201900038 |
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