Akkermansia muciniphila supplementation prevents cognitive impairment in sleep-deprived mice by modulating microglial engulfment of synapses

Akkermansia muciniphila supplementation prevents cognitive impairment in sleep-deprived mice by modulating microglial engulfment of synapses

ABSTRACTThe microbiome-gut-brain axis plays a crucial role in many neurological diseases, including mild cognitive impairment. Sleep deprivation (SD) induces cognitive decline accompanied by alterations in the gut microbiota. However, the role of gut microbiota alterations in SD-induced cognitive dy...

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Bibliographic Details
Main Authors: Na Li, Shuwen Tan, Yue Wang, Jiao Deng, Nan Wang, Shan Zhu, Wen Tian, Jing Xu, Qiang Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Gut Microbes
Subjects:
Sleep deprivation
cognitive dysfunction
microglia
synapse
microbiota-gut-brain axis
Akkermansia muciniphila
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2023.2252764

Internet

https://www.tandfonline.com/doi/10.1080/19490976.2023.2252764

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