Safety of levofloxacin as an antibiotic prophylaxis in the induction phase of children newly diagnosed with acute lymphoblastic leukemia: an interim analysis of a randomized, open-label trial in Brazil

Safety of levofloxacin as an antibiotic prophylaxis in the induction phase of children newly diagnosed with acute lymphoblastic leukemia: an interim analysis of a randomized, open-label trial in Brazil

Background: Despite high cure rates, treatment-related mortality in children with acute lymphoblastic leukemia (ALL) remains significant. About 4% of patients die during remission induction therapy and approximately two-thirds of treatment-related deaths are due to infectious complications. Methods:...

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Bibliographic Details
Main Authors: Mauro Cesar Dufrayer, Ciliana Rechenmacher, Clarice Franco Meneses, Yasmine Massaro Carneiro Monteiro, Fabianne Altruda de Moraes Costa Carlesse, Fabrizio Motta, Liane Esteves Daudt, Mariana Bohns Michalowski
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Brazilian Journal of Infectious Diseases
Subjects:
Acute lymphoblastic leukemia
Pediatric
Fluoroquinolone
Induction
Prophylaxis
Levofloxacin
Online Access:http://www.sciencedirect.com/science/article/pii/S1413867023000053

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http://www.sciencedirect.com/science/article/pii/S1413867023000053

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