8-Hydroxydaidzein Induces Apoptosis and Inhibits AML-Associated Gene Expression in U-937 Cells: Potential Phytochemical for AML Treatment

8-Hydroxydaidzein Induces Apoptosis and Inhibits AML-Associated Gene Expression in U-937 Cells: Potential Phytochemical for AML Treatment

Background: 8-hydroxydaidzein (8-OHD) is a compound derived from daidzein, known for its anti-inflammatory and anti-proliferative properties in K562 human chronic myeloid leukemia (CML) cells. However, its effects on acute myeloid leukemia (AML) cells have not been fully understood. Method: To inves...

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Bibliographic Details
Main Authors: Pei-Shan Wu, Chih-Yang Wang, Hao-Jen Hsu, Jui-Hung Yen, Ming-Jiuan Wu
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Biomolecules
Subjects:
8-hydroxydaidzein
apoptosis
CDK6
caspase-7
acute myeloid leukemia
Online Access:https://www.mdpi.com/2218-273X/13/11/1575

Internet

https://www.mdpi.com/2218-273X/13/11/1575

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