Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors

Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors

The blood-brain barrier (BBB) poses a major obstacle by preventing potential therapeutic agents from reaching their intended brain targets at sufficient concentrations. While transient disruption of the BBB has been used to enhance chemotherapeutic efficacy in treating brain tumors, limitations in t...

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Bibliographic Details
Main Authors: Babu V. Sajesh, Ngoc H. On, Refaat Omar, Samaa Alrushaid, Brian M. Kopec, Wei-Guang Wang, Han-Dong Sun, Ryan Lillico, Ted M. Lakowski, Teruna J. Siahaan, Neal M. Davies, Pema-Tenzin Puno, Magimairajan Issai Vanan, Donald W. Miller
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Pharmaceutics
Subjects:
blood-brain barrier (BBB)
drug delivery
transient modulation
HAV6 cadherin peptide
adenanthin
magnetic resonance imaging (MRI)
medulloblastoma
Online Access:https://www.mdpi.com/1999-4923/11/9/481

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https://www.mdpi.com/1999-4923/11/9/481

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