Frequency of KRAS and BRAF mutations in colorectal carcinoma and their association with clinical-pathological characteristics in a tertiary hospital in Kenya

Frequency of KRAS and BRAF mutations in colorectal carcinoma and their association with clinical-pathological characteristics in a tertiary hospital in Kenya

IntroductionColorectal carcinoma is a leading cause of cancer morbidity and mortality globally. Its management includes the use of targeted therapy which require assessment for biomarkers to choose eligible patients. KRAS and BRAF mutations are biomarkers predictive of response to anti-EGFR therapy....

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Bibliographic Details
Main Authors: Samuel Gakinya, Allan Njau, Abdulkarim Abdallah, Ancent Nzioka, James Ogutu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
Series:Frontiers in Medicine
Subjects:
KRAS
BRAF V600E
colorectal carcinoma
Kenya
Africa
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1433120/full

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https://www.frontiersin.org/articles/10.3389/fmed.2024.1433120/full

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