FUT8 promotes breast cancer cell invasiveness by remodeling TGF-β receptor core fucosylation

FUT8 promotes breast cancer cell invasiveness by remodeling TGF-β receptor core fucosylation

Abstract Background Core fucosylation (addition of fucose in α-1,6-linkage to core N-acetylglucosamine of N-glycans) catalyzed by fucosyltransferase 8 (FUT8) is critical for signaling receptors involved in many physiological and pathological processes such as cell growth, adhesion, and tumor metasta...

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Bibliographic Details
Main Authors: Cheng-Fen Tu, Meng-Ying Wu, Yuh-Charn Lin, Reiji Kannagi, Ruey-Bing Yang
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Breast Cancer Research
Subjects:
Breast cancer
Core fucosylation
EMT
FUT8
Metastasis
TGF-β receptor
Online Access:http://link.springer.com/article/10.1186/s13058-017-0904-8

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http://link.springer.com/article/10.1186/s13058-017-0904-8

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