miR-1202 acts as anti-oncomiR in myeloid leukaemia by down-modulating GATA-1S expression

miR-1202 acts as anti-oncomiR in myeloid leukaemia by down-modulating GATA-1S expression

Transient abnormal myelopoiesis (TAM) is a Down syndrome-related pre-leukaemic condition characterized by somatic mutations in the haematopoietic transcription factor GATA-1 that result in exclusive production of its shorter isoform (GATA-1S). Given the common hallmark of altered miRNA expression pr...

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Bibliografske podrobnosti
Main Authors: Raffaele Sessa, Silvia Trombetti, Alessandra Lo Bianco, Giovanni Amendola, Rosa Catapano, Elena Cesaro, Fara Petruzziello, Maria D'Armiento, Giuseppe Maria Maruotti, Giuseppe Menna, Paola Izzo, Michela Grosso
Format: Article
Jezik:English
Izdano: The Royal Society 2024-02-01
Serija:Open Biology
Teme:
alternative splicing
Down syndrome
GATA-1
miR-1202
myeloid leukaemia
Online dostop:https://royalsocietypublishing.org/doi/10.1098/rsob.230319

Internet

https://royalsocietypublishing.org/doi/10.1098/rsob.230319

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