Molecular Modeling and Synthesis of New HIV Latency-Reversing Agents Targeting the Lymphatic System

During the HIV infection, a small amount of the virus remains in a latent state, forming a viral reservoir in places with limited access to drugs such as lymph nodes. HIV latency reversing agents, as HDAC inhibitors, have been used in the “kick and kill” strategy aiming to reactivate the latent viru...

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Bibliographic Details
Main Authors: Beatriz Meduqui Rodrigues, Juliana Romano Lopes, Andressa Francielli Bonjorno, Jean Leandro dos Santos
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Medical Sciences Forum
Subjects:
Online Access:https://www.mdpi.com/2673-9992/14/1/3