Vaccination of Gilthead Seabream After Continuous Xenoestrogen Oral Exposure Enhances the Gut Endobolome and Immune Status via GPER1

In fish culture settings, the exogenous input of steroids is a matter of concern. Recently, we unveiled that in the gilthead seabream (Sparus aurata), the G protein-coupled estrogen receptor agonist G-1 (G1) and the endocrine disruptor 17α-ethinylestradiol (EE2) are potent modulators in polyreactive...

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Main Authors: Pablo Castejón, Isabel Cabas, Victoria Gómez, Elena Chaves-Pozo, Isabel Cerezo-Ortega, Miguel Ángel Moriñigo, Eduardo Martínez-Manzanares, Jorge Galindo-Villegas, Alfonsa García-Ayala
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.742827/full