Vaccination of Gilthead Seabream After Continuous Xenoestrogen Oral Exposure Enhances the Gut Endobolome and Immune Status via GPER1

Vaccination of Gilthead Seabream After Continuous Xenoestrogen Oral Exposure Enhances the Gut Endobolome and Immune Status via GPER1

In fish culture settings, the exogenous input of steroids is a matter of concern. Recently, we unveiled that in the gilthead seabream (Sparus aurata), the G protein-coupled estrogen receptor agonist G-1 (G1) and the endocrine disruptor 17α-ethinylestradiol (EE2) are potent modulators in polyreactive...

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Bibliographic Details
Main Authors: Pablo Castejón, Isabel Cabas, Victoria Gómez, Elena Chaves-Pozo, Isabel Cerezo-Ortega, Miguel Ángel Moriñigo, Eduardo Martínez-Manzanares, Jorge Galindo-Villegas, Alfonsa García-Ayala
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
16S rRNA
endocrine disruptors (EDCs)
endobolome
estrogens
fish
G protein-coupled receptor 1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.742827/full

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