Intracellular Ca2+ dynamics in the ALA neuron reflect sleep pressure and regulate sleep in Caenorhabditis elegans

Summary: The mechanisms underlying sleep homeostasis are poorly understood. The nematode Caenorhabditis elegans exhibits 2 types of sleep: lethargus, or developmentally timed, and stress-induced sleep. Lethargus is characterized by alternating cycles of sleep and motion bouts. Sleep bouts are homeos...

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Bibliographic Details
Main Authors: Shinichi Miyazaki, Taizo Kawano, Masashi Yanagisawa, Yu Hayashi
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222007234