The Role of Genetic and Epigenetic Regulation in Intestinal Fibrosis in Inflammatory Bowel Disease: A Descending Process or a Programmed Consequence?

The Role of Genetic and Epigenetic Regulation in Intestinal Fibrosis in Inflammatory Bowel Disease: A Descending Process or a Programmed Consequence?

Inflammatory bowel diseases (IBDs) are a group of chronic diseases characterized by recurring periods of exacerbation and remission. Fibrosis of the intestine is one of the most common complications of IBD. Based on current analyses, it is evident that genetic factors and mechanisms, as well as epig...

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Bibliographic Details
Main Authors: Sara Jarmakiewicz-Czaja, Aneta Sokal, Katarzyna Ferenc, Elżbieta Motyka, Kacper Helma, Rafał Filip
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Genes
Subjects:
Crohn’s disease
epigenetic factors
intestinal fibrosis
<i>NOD2</i>
<i>TGFβ</i>
ulcerative colitis
Online Access:https://www.mdpi.com/2073-4425/14/6/1167

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https://www.mdpi.com/2073-4425/14/6/1167

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