Phenotypic heterogeneity in modeling cancer evolution.

The unwelcome evolution of malignancy during cancer progression emerges through a selection process in a complex heterogeneous population structure. In the present work, we investigate evolutionary dynamics in a phenotypically heterogeneous population of stem cells (SCs) and their associated progeni...

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Bibliographic Details
Main Authors: Ali Mahdipour-Shirayeh, Kamran Kaveh, Mohammad Kohandel, Sivabal Sivaloganathan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5662227?pdf=render