Control of Helicobacter pylori with engineered probiotics secreting selective guided antimicrobial peptides

ABSTRACT Helicobacter pylori is the primary cause of 78% of gastric cancer cases, providing an opportunity to prevent cancer by controlling a single bacterial pathogen within the complex gastric microbiota. We developed highly selective antimicrobial agents against H. pylori by fusing an H. pylori-b...

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Bibliographic Details
Main Authors: Ankan Choudhury, Patrick S. Ortiz, Mikaeel Young, Md. Toslim Mahmud, Ryan T. Stoffel, K. Leigh Greathouse, Christopher M. Kearney
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:Microbiology Spectrum
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02014-23