Gold(III)-Catalyzed Propargylic Substitution Reaction Followed by Cycloisomerization for Synthesis of Poly-Substituted Furans from <i>N</i>-Tosylpropargyl Amines with 1,3-Dicarbonyl Compounds

Gold(III)-Catalyzed Propargylic Substitution Reaction Followed by Cycloisomerization for Synthesis of Poly-Substituted Furans from <i>N</i>-Tosylpropargyl Amines with 1,3-Dicarbonyl Compounds

The treatment of <i>N</i>-tosylpropargyl amines <b>1</b> with 1,3-dicarbonyl compounds <b>2</b> in the presence of AuBr<sub>3</sub> (5 mol%) and AgOTf (15 mol%) afforded poly-substituted furans <b>3</b> in good-to-high yields via the gold-c...

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Bibliographic Details
Main Authors: Nobuyoshi Morita, Shingo Uchida, Hitomi Chiaki, Naho Ishii, Kentaro Tanikawa, Kosaku Tanaka, Yoshimitsu Hashimoto, Osamu Tamura
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Molecules
Subjects:
gold catalyst
poly-substituted furans
<i>N</i>-tosylpropargyl amines
propargylic substitution
cycloisomerization
Online Access:https://www.mdpi.com/1420-3049/29/2/378

Internet

https://www.mdpi.com/1420-3049/29/2/378

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