Activity of clinically relevant antimalarial drugs on Plasmodium falciparum mature gametocytes in an ATP bioluminescence "transmission blocking" assay.

BACKGROUND: Current anti-malarial drugs have been selected on the basis of their activity against the symptom-causing asexual blood stage of the parasite. Which of these drugs also target gametocytes, in the sexual stage responsible for disease transmission, remains unknown. Blocking transmission is...

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Bibliografske podrobnosti
Main Authors: Joël Lelièvre, Maria Jesus Almela, Sonia Lozano, Celia Miguel, Virginia Franco, Didier Leroy, Esperanza Herreros
Format: Article
Jezik:English
Izdano: Public Library of Science (PLoS) 2012-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC3325938?pdf=render